PRP Therapy for Female Infertility: Does It Work? 2026 Review

KEY TAKEAWAYS

• PRP (Platelet-Rich Plasma) therapy uses growth factors from the patient’s own blood to stimulate tissue repair and regeneration.
• Intra-ovarian PRP is used for poor ovarian responders and premature ovarian insufficiency with promising early results.
• Intra-uterine PRP improves endometrial thickness in women with thin endometrium who have failed prior IVF transfers.
• PRP therapy cost in Pune ranges from INR 15,000 to INR 35,000 per session.
• Evidence is emerging and promising but PRP is still considered adjunct rather than first-line; discuss with your specialist.
• Dr. Bhagyashri Naphade at La Femme Fertility Clinic, Wakad, offers PRP as part of individualised fertility protocols.

PRP therapy for female infertility is one of the more exciting developments in reproductive medicine over the past decade. For women with poor ovarian response or recurrent implantation failure due to thin endometrium, it offers a potential additional tool when standard protocols have not worked.

This 2026 review by Dr. Bhagyashri Naphade at La Femme Fertility Clinic, Wakad, summarises the current clinical evidence and explains who in Pune might genuinely benefit from this treatment.

Quick Facts: PRP Therapy for Infertility in Pune

Parameter	Details
PRP session cost in Pune	INR 15,000 to INR 35,000 per session
Number of sessions typically	1 to 3 per treatment cycle
PRP for poor ovarian response	Improving AMH and follicle count in selected cases
PRP for thin endometrium	Improving lining thickness before FET
Evidence status	Emerging; adjunct therapy; not standalone first-line
Available at La Femme, Wakad	Yes

PRP Fertility Research: Key Evidence 2024–2026

Study Area	Finding	Source
Intra-ovarian PRP in poor responders	Improved AMH and AFC in select patients after treatment	PubMed-indexed studies 2022-2024
PRP for thin endometrium (<7mm)	Endometrial thickness improved in 60 to 70 percent of cases	Industry research estimate
PRP and IVF outcomes	Improved clinical pregnancy rates in poor responder sub-groups	Published fertility journal data
Safety profile	No significant adverse events reported in published studies	Reproductive medicine literature
Limitations	Small sample sizes; lack of large RCTs; results variable	Academic consensus 2024

What Is PRP and How Is It Prepared?

Platelet-Rich Plasma is prepared by drawing approximately 20 to 30mL of the patient’s own blood and spinning it in a centrifuge to concentrate the platelets. Platelets contain growth factors including PDGF, VEGF, IGF and TGF-beta that stimulate cellular repair and tissue regeneration. The concentrated PRP is then injected into the target tissue.

Because PRP uses the patient’s own blood, there is no risk of rejection or allergic reaction. The procedure is relatively simple and takes 45 to 60 minutes in total including blood draw, centrifugation and injection.

Intra-Ovarian PRP: Who May Benefit?

Intra-ovarian PRP is most studied in women with poor ovarian reserve (low AMH, low AFC), premature ovarian insufficiency (POI) and poor responders in previous IVF cycles who retrieved fewer than 3 to 4 eggs despite standard stimulation. The hypothesis is that PRP growth factors stimulate dormant follicles and improve the ovarian microenvironment.

Early studies, including those published in PubMed-indexed reproductive medicine journals, show improvements in AMH levels and antral follicle counts in a proportion of treated women. However, results vary and not all patients respond. Your specialist will assess whether your case profile is likely to benefit before recommending the procedure.

Intra-Uterine PRP: Thin Endometrium Treatment

A uterine lining of at least 7mm is generally needed for embryo implantation. Women with chronic thin endometrium, often from previous uterine surgeries, infections or poor blood supply, who have failed prior FET cycles are candidates for intra-uterine PRP infusion. The PRP is introduced into the uterine cavity through a thin catheter, similar to an embryo transfer procedure.

Published data suggests endometrial thickness improved in 60 to 70 percent of cases treated with intra-uterine PRP, with subsequent improvement in implantation rates in some studies. Results are encouraging but further large-scale research is ongoing.

PRP Therapy Cost in Pune 2026

PRP Application	Sessions Typically	Cost Per Session	Total Estimated Cost
Intra-ovarian PRP	1 to 2	INR 20,000 to INR 35,000	INR 20,000 to INR 70,000
Intra-uterine PRP	1 to 3	INR 15,000 to INR 25,000	INR 15,000 to INR 75,000
PRP + IVF cycle (combined)	Part of IVF protocol	As above	Adds to IVF cycle cost
Follow-up AMH or ultrasound	Per visit	INR 500 to INR 2,000	2 to 3 follow-up visits

Is PRP Covered Under Insurance or Ayushman Bharat?

PRP therapy for fertility is not currently covered under Ayushman Bharat or most standard Indian health insurance policies. It is considered an experimental adjunct treatment and is usually an out-of-pocket expense. Discuss the potential benefit vs cost with your specialist before proceeding.

Conclusion

PRP therapy for female infertility in Pune represents a genuinely promising adjunct treatment for women with poor ovarian reserve and thin endometrium who have not responded adequately to standard protocols. The evidence is encouraging but still evolving, and the best results come when PRP is integrated thoughtfully into a comprehensive fertility plan.

If you are a poor responder or have had repeated implantation failures, book a consultation with Dr. Bhagyashri Naphade at La Femme Fertility Clinic, Wakad, to assess whether PRP therapy is right for your specific case.

Frequently Asked Questions

Medical Disclaimer: This article is for informational purposes only and does not constitute professional medical advice. Always consult a qualified doctor before making healthcare decisions. Costs are indicative and may vary.